Found 50 of ic50 for Anti-estrogen binding site (AEBS)having polymerids = 50001269,50006184 and
complexids = 50000409
Affinity DataIC50: 0.100nMAssay Description:Antagonistic activity for carbachol induced contractions in guinea pig ileum against Muscarinic acetylcholine receptor M3 in the presence of mepyrami...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 2.30nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Antagonistic affinity tested against isolated Rat Thoracic Aorta Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 9.40nMAssay Description:Antagonistic affinity tested against isolated Rat Thoracic Aorta Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/7-dehydrocholesterol reductase(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site (AEBS)More data for this Ligand-Target Pair
3D Structure (crystal)Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/7-dehydrocholesterol reductase(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site (AEBS)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Tetsed for Antagonistic activity at histamine H3 receptor in guinea pig ileal longitudinal muscle in the presence of mepyramine at a concentration of...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 30nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
Target3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase/7-dehydrocholesterol reductase(Homo sapiens (Human))
University of Georgia
Curated by ChEMBL
University of Georgia
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site (AEBS)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 50nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Antagonistic affinity tested against isolated Rat Thoracic Aorta Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 120nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 188nMAssay Description:In vitro relative antagonist potency towards guinea pig Tachykinin receptor 1More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 200nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 303nMAssay Description:Antagonistic affinity tested against isolated Rat Prostatic Vas Deferens Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro relative antagonist potency towards guinea pig Tachykinin receptor 2More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.07E+3nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.39E+3nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 2.00E+3nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of delta8,7-sterol isomerase-mediated cholesterol biosynthesis in human HL60 cells assessed as increase in zymostenol accumulationMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 5.00E+4nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
